High level overview of ancestry DNA & 23andme raw data interpretation

23andme raw data analysis

Gone are the days of generating endless reports covering many topics; some are relevant, and most invite fear and confusion. Today, good genetic service is moving towards a more personalized experience. 

Genetics reveals one size doesn't fit all; having your 23andme raw data interpretation is only half the battle. The other half? It is to analyze your 23andme raw data or ancestry DNA in a meaningful way. And in many ways, that's much harder to get by.

When it comes to uploading your DNA raw data for interpretation, you've got many choices. A lot of options. Depending on the topics you want to learn more about, you could be entering a veritable information war — a war with hundreds of data points. To get the best results — and ideally, win — that information war, you'll need to think about how relevant this information is for you. But the first and most important thing to remember is that you should never look at 23andme or ancestry raw data by itself— because there are many other factors at play. We'll talk about it next.

How to access your ancestry DNA & 23andme raw data for interpretation

Downloading 23andme raw data or ancestry DNA data, or any other genetic service is a simple process. After your reports are ready, you can download a copy of your raw data. Most of the time, your raw DNA data will be in txt format. You can easily convert it to a csv file by clicking save as filename.csv. Genetic genealogy, traits, and disease risk are popular applications. 

23andme raw data analysis

The process

Think of the human genome as a lengthy account that contains roughly 20,000 genes. In some cases, the spelling variations create genes with different interpretations— genes that code for different proteins. Other spelling variations appear not to affect whatsoever, at least not ones that today's scientists know how to measure. The DNA sample gets genotyped to look for genetic variations; SNPs single nucleotide polymorphisms. The second step compares your set of SNPs to known reference groups. Then a computer program takes over.

In the case of Genetic genealogy, it looks for the best fit to determine ancestry percentages. DNA testing can be used with genealogical and historical records to uncover deep ancestry hundreds of years into the past and geographical origins. Another use of DNA results is to measure if two individuals share autosomal DNA to determine relatedness. Remember, ancestry is not the same as heritage.

Data from DNA results can lead to useful information about inherited health risks. What will the test tell you exactly? 

The results of tests to predict disease risk do not provide a definite yes or no answer (in the vast majority of the cases) about whether a person will develop a given disease. Other factors, including genetic variations that did not get tested, environmental factors, and lifestyle choices (such as diet and exercise), also contribute to disease risk in ways that are not fully understood. Therefore, a result showing an increased risk does not mean you will develop the disease. A result showing a reduced risk does not mean you will never develop the disease. Talk to a healthcare professional if you have questions, do not invite fear or panic.

How to choose

We believe that the various genetic platforms available online should optimize their technology for humans who use their website. After all, personalized genetic analysis exists for humans. Some of the world's top scientists optimized DNA science to serve human beings the most relevant, helpful reports based on their uploaded raw DNA data.

Plus, you should take scientific evidence into account when choosing a service, so above all else, you should select a service that: 

1 Clearly and helpful in answering people's questions.

2 Take your privacy seriously — uploaded raw DNA data file is deleted when your reports are ready.

In short, there's a straightforward key to happier and healthier: provide people with useful and personalized content. At citochrome, we believe that while it's still important to do research and have proper raw DNA data analysis, it's even more important to focus on two things: How to make people happier and healthier To give people something to think about

We hope you're well

The current events have turned every potential stressor in our lives up a notch, causing unprecedented anxiety and isolation levels. For everyone pushing through depression quietly, get help. Maybe you've felt not at ease or just not feeling like yourself. Your body can hint to you when something is wrong, even before your conscious mind becomes aware. The good news is, help is all around you. Reach out to a trusted friend or colleague, or find an online support network. 

There are actions we can take every day to help ourselves. All of us should get enough sleep, eat well, and exercise regularly. These are the three basic things that all of us can do to take care of our physical and mental health. 

pharmacogenetics

Next steps

After all, Your health is your most valuable asset. With tools like citochrome, it's never been easier to get more out of your DNA raw data in a personalized and useful way.

Your DNA results from Direct to Consumer genetic tests analyze hundreds of thousands of genetic variations. Some of those genetic variations are genes encoding cytochrome P450 enzymes. The CYP 450 are a group of enzymes that have important clinical implications for drug metabolism. CYP2C19 enzyme contributes to the metabolism of many drug classes such as antidepressants, benzodiazepines, proton pump inhibitors, and other essential prescription drugs. There are four metabolizer classes of this enzyme; UltraRapid, Normal metabolizer, Intermediate and poor metabolizer.

Drug metabolizing enzymes determine how quickly a medication (drug) is broken down (metabolized). Some medicines might not work as expected if they're metabolized too quickly or can cause side effects if they get metabolized too slowly.

On the other hand, some medications need to get metabolized to work. Slow metabolizers might not get the expected therapeutic effect, and fast metabolizers are at increased risk of side effects.

If you want better insights that can inform your health provider about how you may break down certain medications commonly prescribed to treat pain, depression, anxiety, and other conditions. Citochrome provides low cost  ancestry DNA & 23andme raw data interpretation.

You should choose the service that also helps improve the clarity and helpfulness of your DNA results so that you can optimize for better health and privacy at the same time.

Stay Healthy


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